Medications of Parkinson’s Disease

07 Mar
2019
By Marie

Numerous medications are available for the management of symptoms of Parkinson’s disease. All of these are specially formulated to ease symptoms and improving quality of life. Currently, there is no cure or therapy that has been proven to stop disease progression.

Medications are the key to control the symptoms of Parkinson’s. The symptoms of Parkinson’s develop when the level of dopamine (a chemical messenger), falls in the brain. Parkinson’s medications aim to increase the level of dopamine that helps in the stimulation of certain parts of the brain where dopamine functions. Current drug treatment can help to reduce the symptom; there is a treatment that can cure or stop the progression of this is a neurological condition.

Medications are specific to you

Every individual suffering with Parkinson’s disorder has a different condition, he/she experience different symptoms so, your health care specialist will find the treatment that works best for you after determining the condition of the patient. It takes time to find the best drug treatment. The appropriate dose and best timings, your health care specialist will need to do some changes along the way. Parkinson’s symptoms tend to change over time, due to which change of medication is required. The drug treatment will start at low doses and increased gradually. Your health care provider will gradually step up the dose, increases the frequency, or may introduce new medications to the treatment until you gain control over your symptoms. If you observe any changes or progression in your symptoms, it is important not to make any changes in your medication, or the treatment regimen without talking to your health care provider.

Medications for Parkinson’s

Drug treatment may help you manage problems with movements, and it can improve walking pattern and tremors. One can find a significant improvement after beginning Parkinson’s drug therapy. Medications that your health care provider may prescribe include:

  • Carbidopa-Levodopa- One of the most effective medication, when it comes to managing Parkinson’s symptoms is Levodopa. It works as a natural chemical in your brain that passes and converted to dopamine in the brain. Levodopa is prescribed with Carbidopa, which stops levodopa to convert into dopamine early in the brain.
  • Dopamine agonists- Th medications coms und this class of drugs don’t convert into dopamine, thy act like dopamine in the brain. In other words, we can say that they mimic the effects of dopamine in the brain.
  • MAO inhibitors- These medications are helpful in break down of dopamine, by inhibiting MAO B enzyme, which metabolizes dopamine in the brain.
  • Anticholinergics- These are extremely beneficial in controlling tremors associated with Parkinson’s.

The working mechanism of Parkinson’s disease

As mentioned above, the chemical messenger called dopamine is produced in the brain, which plays a crucial role in bin functioning and sending signals to other parts of the body. The symptoms of Parkinson’s develop when there is very less amount of dopamine in the brain. The low levels of dopamine may be because of the death of the cells in your brain that are responsible for producing dopamine. Most of Parkinson’s medications are administered to increase the levels of dopamine in your brain. Some acts as a substitute for the chemical messenger by stimulation the brain part where dopamine acts. The drugs also block the action of certain enzymes that lead to dopamine break down.

Understanding your drug therapy

Ask your health care provider if there is anything related to the use of your drug treatment that you don’t understand. Your health care provider will briefly explain you everything related to your dose regimen. You can even ask for written information, and they would not mind. Make sure you know everything about your Parkinson’s medications. You should know what to do if you mistakenly miss a dose. However, it will be good for your health not to miss any dose. Remember the thing that Everyone with Parkinson’s is different so it is not possible that your medication, dose, and timings should be the same as someone you know with the condition.

Share decisions with your health care provider about your medications

It is important to let your health care provider know if you are suffering from any other medical condition, or if you think you have conceived. You must tell your health care specialist about any side effects if you are experiencing with your Parkinson’s medication that you are taking to ease the symptoms. Do not discontinue or stop taking the drug until you have spoken to your health care provider s this can be life-threatening. 

Parkinson Disease Early Symptoms

27 Feb
2019
By Marie

Parkinson’s disease is most recognized in its later stages. Tremors and difficulty walking are the most symptoms. But the truth is this neurological disorder is tough to diagnose at its early stages. Physicians are unable to spot most cases until they have crossed the initial stages. So, is there any way out there any trick to identify symptoms earlier and get the treatment the right time? Yes, but it is important to know what to look for.

Parkinson’s disease is a progressive brain disorder, the signs are difficult to pinpoint at earlier stages. The symptoms of Parkinson’s disease could indicate many problems, which makes early diagnosis difficult. This is the reason why people with Parkinson’s disease got frustrated while searching for reasons behind their movement problems. However, there are some signs that could alert you and allow you to get the treatment earlier.

When to consult a physician?

Not all the symptoms are experienced by Parkinson’s patient which leads to confusion in diagnosis. Consult a physician, if you or your loved one experience any of the symptoms given below:

  • Tremors or shaking- An intermittent shaking in your finger, lips, chin, hand, leg, or tongue are an indication of Parkinson’s. Experts and physicians consider tremors to be a crucial sign of the disease. Facial twitching or limb shaking are persistent in patients with Parkinson’s. Tremors gradually worsen as the disease progresses. The tremors stop when the patient uses the affected part of the body.
  • Difficulty walking- Changes in the walking patterns of an individual could be an early sign of Parkinson’s disease. Dragging feet should not be ignored. An individual dealing with Parkinson’s might walk slow or drag their feet while walking. The affected person might walk at an irregular pace, they might suddenly walk faster or slower.
  • Changes in handwriting- Many individuals who are affected with Parkinson’s find that their handwriting has changed, they may notice that your letter suddenly becomes very small.
  • Loss of smell- The condition may also be referred to as olfactory dysfunction where an individual with Parkinson’s losses their ability to smell. It is one of the common symptoms of Parkinson’s disease and affects almost 70 to 90% of Parkinson’s sufferers. Apart from movement problems, loss of smell is easy to recognize in most patients. It can be an early indication as it develops several years before the disease affects an individual. People who have Parkinson’s disease may experience a dull sense of smell, difficulty identifying odors, difficulty telling the difference between odors. However, having a loss of smell does not always means that an individual is affected by Parkinson’s disease. Other factors such as smoking and exposure to harmful chemicals may also contribute to changes in the smell.
  • Disturbed sleeping patterns- Sleeping problems can give rise to many health issues, Parkinson’s disease is one of them which can affect the sleeping patterns of a Parkinson’s sufferer. An affected individual may suffer from any of the sleeping issues including:
  • Excessive daytime fatigue
  • Insomnia
  • Sleep apnea
  • Uncontrolled or sporadic movements
  • Nightmare
  • Narcolepsy
  • Constipation- Constipation could be an early indication of Parkinson’s disorder. However, it is a commonly reported issue even in healthy people. But the fact is, people with Parkinson’s are more likely to affected by constipation. If you suddenly have constipation even after following a healthy diet plan, it is time for you to consider a health care specialist and to get a check.
  • Poor balance- Parkinson’s disease is believed to affect nerve cells called basal ganglia, present in the brain. According to researchers, the nerves control balance and flexibility, so any kind of damage to these nerves can be harmful and affect ka an individual’s balance.
  • Facial masking- Most clinical research found that people with Parkinson’s disease used to develop a reduced ability to make facial expressions which are other words called as facial masking. During the condition, the facial muscles begin to move slower than they do normally. People having this condition may appear emotionless even after feeling emotions. Such people tend to blink eyes slower than normal. This also another change that can be recognized in most people with Parkinson’s disease. An affected person may find difficulty in communicating with others because changes in the expressions cause trouble communicating.
  • Vocal changes- Change in the quality of a person’s voice is another indication of Parkinson’s disorder. The changes may involve, talking in a softer tone, start the conversation in a usual volume than the voice becomes gradually softer and even fades away in some cases. Some people appeared to have a monotonous voice, they don’t have variations in the volume and tone of their voice.
  • Weight loss- Affected person’s experience mild to moderate weight loss for several reasons, Parkinson’s disease may be one of them. Depression, digestive issues, and people tendency to eat less may contribute to weight loss.

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2015
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2015
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