Bimatoprost Ophthalmic Solution for Glaucoma

24 Jul
2017
By Marie

There are many effective eye drops available to treat glaucoma, which is defined by elevated internal eye pressure, called intraocular pressure. Medicated ophthalmic solutions are formulated to use twice daily to lower internal pressure in order to prevent optic nerve damage.

Bimatoprost is a pharmaceutical ingredient used for the reduction of elevated pressure (IOP) in patients with occular hypertension and open angle glaucoma. It is a synthetic prostamide analog which exerts its mode of action by mimicking the effects of naturally occurring chemical prostamides. It has been demonstrated that the active ingredient lowers intraocular pressure by increasing the out flow of aqueous fluid secreted by the eye.

The action of Bimatoprost:

Bimatoprost is a saturated fatty acid, similar to hormones. It is supplied as an active ingredient in the form of eye drops to treat glaucoma. The solution is instilled into the eye to help maintain the balance of inflow and outflow of ocular fluid in the eye. The active agent is known to accelerate the reduction of intraocular pressure and reduces the pressure to the eyes. It is an ideal option to lower raised pressure within your eyes.

Many people call this a cosmetic ingredient and often use it for increasing the length of the eyelashes.

Adverse effects of Bimatoprost ophthalmic solution

In clinical trials, adverse effects occurring in approximately 15% to 45% of patients included the following:

  • Ocular pruritis
  • Conjunctival hyperaemia

Some rare adverse effects include the following:

  • Eye pain
  • Pigmentation of the periocular skin
  • Visual disturbance
  • Ocular burning
  • Foreign body sensation
  • Eyelash darkening
  • Ocular dryness
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